Determination of acetylsalicylic acid in aspirin using Total Fluorescence Spectroscopy

1.0 Introduction: Aspirin is a common over the counter drug. You will develop an analytical method to monitor this in standard capsules and in urine using fluorescence. The analysis of aspirin by spectroscopic means is a common introductory lab. However, modifying this for use with biological materials requires a deeper understanding. One specific problem arises from the fact that many biological materials are considered biological waste and therefore require documented and approved protocols to deal with these materials. Given this the analytical team needing to conduct proof of concept studies face either a long process to get appropriate approval or the task of developing an appropriate synthetic matrix.